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RH BLOOD GROUP SYSTEM Most complex blood group, nearly 50 different Rh antigenic specificities have been identified Discovery Levine and Stetson → OB patient who gave birth to a stillborn baby (HDN) She showed hemolytic transfusion reaction when transfused with husband's blood The Ab isolated from mother's serum reacted both at 37 0 C and 0 C with husband'sAntif is a compound antibody directed against the c and e antigens when both antigens are present on the same haplotype (ce) Blood for transfusion must be either c or e AntiG is an antibody directed against the G antigen in the Rh blood group system The G antigen is found on red cells possessing C or D antigenSeveral nomenclatures have been used to describe antigens, proteins, and genes in the Rh system Throughout this review, we will use traditional terminology recommended by the International Society of Blood Transfusion (ISBT) committee for terminology of blood group antigens5 The numeric portion of the ISBT terminolog...

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